Medication treatment of obesity
should be used only in patients who have health risks related to obesity.
Medications should not be used for cosmetic reasons.
Like
diet and exercise, the goal of medication treatment has to be realistic. With
successful medication treatment, one can expect an initial weight loss of at
least 5 pounds during the first month of treatment, and a total weight loss of
10%-15% of the initial body weight. The first class (category) of medication
used for weight control cause symptoms that mimic the sympathetic nervous
system. As a result, the major side effect of this class of medication is high
blood pressure.
Phentermine
The
common side effects of phentermine include headache,
insomnia, irritability, and nervousness.
Fenfluramine (the fen of fen/phen) and dexfenfluramine (Redux) suppress
appetite mainly by increasing release of serotonin by the cells. Phentermine
alone is still available for treatment of obesity but only on a short-term
basis (a few weeks).
Sibutramine (Meridia)
a
drug which increases the levels of serotonin and norepinephrine in the brain,
to treat obesity (both in attaining and in maintaining weight loss).


